Which symptom could indicate cystic fibrosis in a newborn?

Cystic fibrosis is a genetic disorder that affects the exocrine glands, leading to the production of thick, sticky mucus in various organs, especially the lungs and digestive system. In newborns, one of the classic early signs of cystic fibrosis is meconium ileus, which occurs when the thickened meconium obstructs the intestines shortly after birth. Bilious vomiting further indicates this obstruction, as bile is unable to flow properly through the intestine, leading to vomiting of greenish fluid.

The presence of meconium ileus and bilious vomiting in a newborn strongly suggests cystic fibrosis, as this symptom combination is highly indicative of the disease. The diagnosis is usually followed up with confirmatory tests, but recognizing these early gastrointestinal symptoms is crucial for timely intervention and management of cystic fibrosis in affected infants.