Which of the following is a complication of Marfan's syndrome?

Marfan's syndrome is a genetic disorder that affects the connective tissue in the body, leading to a range of potential complications, particularly involving the cardiovascular system, skeletal system, and eyes. One known complication of this syndrome is the risk of spontaneous pneumothorax, which occurs when air leaks into the space between the lung and the chest wall, causing the lung to collapse. This can happen in individuals with Marfan's syndrome due to the underlying factors such as those related to abnormal connective tissue, which can affect the lung structure and the pleura.

The association with spontaneous pneumothorax is significant because patients with Marfan's syndrome can develop abnormalities in the lung architecture and the pleural space, increasing their susceptibility to this life-threatening condition. Spontaneous pneumothorax is an important clinical consideration, especially in young adults with Marfan's, as it can be abrupt in onset and may require urgent medical intervention.

Other options, while they may present in various contexts, are not direct complications of Marfan's syndrome. Hearing loss, gastroenteritis, and cystic fibrosis do not have established links to the physiology or pathophysiology of Marfan’s and are generally part of different medical conditions or syndromes not associated with connective tissue