Which combination of symptoms characterizes Hemolytic Uremic Syndrome (HUS)?

Hemolytic Uremic Syndrome (HUS) is primarily characterized by a classic triad of symptoms: hemolytic anemia, thrombocytopenia (low platelet count), and acute renal failure. The choice that includes hemolysis, low platelets, and neurological deficits describes a broader spectrum of potential complications associated with severe forms of HUS but acknowledges that patients can present with neurological manifestations in some instances, particularly in post-diarrheal HUS often linked to Shiga toxin-producing E. coli.

Including fever is notable because while it can be part of various infections, it is not specific to HUS itself. The neurological deficits can arise due to the systemic effects of the toxins and the resultant complications, thus making this selection the best choice, as it encapsulates the key components of the syndrome along with potential complications that reflect its severity and multi-system involvement.

The other choices either lack critical elements of the defining triad of HUS or include symptoms not typically associated with the condition. For instance, elevated liver enzymes and gastrointestinal disturbances are more common in other syndromes and do not specifically represent the classic presentation of HUS, which focuses on hemolysis and renal impairment along with thrombocytopenia.