What is a possible physical characteristic associated with Down syndrome?

A flat occiput is indeed a recognized physical characteristic associated with Down syndrome, which is caused by the presence of an extra copy of chromosome 21. Children with Down syndrome often exhibit certain distinct physical features, one of which is a flat back of the head (flat occiput). This characteristic can contribute to the overall appearance associated with the condition, including a shorter stature and a broad, rounded face.

The other characteristics listed do not specifically align with the common physical traits associated with Down syndrome. For example, a high arched palate can occur in various conditions, but it is not a hallmark feature of Down syndrome. A long neck is typically not observed in children with Down syndrome; instead, they may have a shorter neck. Similarly, large hands can be seen in various genetic conditions but are not a defining characteristic of Down syndrome, where hands often appear shorter with stubby fingers. Understanding these typical phenotypic manifestations is crucial for recognizing the clinical features associated with this genetic condition.