What is a hallmark physical feature of Marfan syndrome?

In Marfan syndrome, arachnodactyly, or "arachnoid fingers," is a hallmark physical feature. This characteristic refers to long and slender fingers and toes, which are often disproportionate in relation to the person's body size. The term comes from what appears to be a spider-like appearance, reflecting the long, thin fingers and the overall elongation of the limbs that are associated with the disorder.

Marfan syndrome is a connective tissue disorder that can lead to various skeletal, cardiovascular, and ocular manifestations. The presence of arachnodactyly is often assessed using the criteria established by Ghent, which includes the morphologic findings in addition to family history and other systemic complications caused by the underlying pathology in connective tissues.

The other options listed do not accurately represent the distinctive features of Marfan syndrome. For instance, macrocephaly and thickened skin are not typical characteristics associated with this condition. Individuals with Marfan syndrome usually exhibit tall stature rather than short stature, contrasting with other growth-related disorders. Thus, understanding the emphasis on arachnodactyly is crucial when identifying physical features associated with Marfan syndrome.