In Thrombotic Thrombocytopenic Purpura (TTP), which of the following symptoms is typically observed?

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In Thrombotic Thrombocytopenic Purpura (TTP), fever and behavioral changes are indeed characteristic symptoms. TTP is a microangiopathic hemolytic anemia that can lead to a range of systemic problems due to the formation of blood clots in small blood vessels, leading to a pentad of symptoms: thrombocytopenia, microangiopathic hemolytic anemia, neurological symptoms, renal dysfunction, and fever.

The presence of fever can indicate an ongoing inflammatory or infectious process, which can be secondary to the underlying pathology. Behavioral changes, encompassing confusion, lethargy, or seizures, are part of the neurological symptoms associated with TTP, stemming from cerebral involvement due to small vessel occlusion.

Other options, while they may present in different contexts or related conditions, are not characteristic of TTP specifically. Gastrointestinal bleeding, chest pain, dyspnea, rash, and jaundice might occur but are typically related to other hematological or systemic disorders rather than being definitive signs of TTP itself. Thus, the presence of fever and behavioral changes provides clearer insight into the clinical picture of TTP.

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